Publications

2017

Lu, A. T., Hannon, E., Levine, M. E., Crimmins, E. M., Lunnon, K., Mill, J., Geschwind, D. H. & Horvath, S. (2017). Genetic architecture of epigenetic and neuronal ageing rates in human brain regions. Nat Commun 8, 15353.

Hannon, E., Weedon, M., Bray, N., O’Donovan, M. & Mill, J. (2017). Pleiotropic Effects of Trait-Associated Genetic Variation on DNA Methylation: Utility for Refining GWAS Loci. Am J Hum Genet.

T M Murphy, B Crawford1, E L Dempster, E Hannon, J Burrage, G Turecki, Z Kaminsky and J Mill. Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide. Translational Psychiatry. 2017 Jan. 7, e989; doi:10.1038/tp.2016.249

2016

Joana Viana; Eilis Hannon; Emma Dempster; Ruth Pidsley; Ruby Macdonald; Olivia Knox; Helen Spiers; Claire Troakes; Safa Al-Saraj; Gustavo Turecki; Leonard C Schalkwyk; Jonathan Mill. Schizophrenia-associated methylomic variation: molecular signatures of disease and polgenic risk burden across multiple brain regions. Hum Mol Genet. December 2016. DOI: 10.1093/hmg/ddw373

Traylor, M., Malik, R., Nalls, M. A., Cotlarciuc, I., Radmanesh, F., Thorleifsson, G., Hanscombe, K. B., Langefeld, C., Saleheen, D., Rost, N. S., Yet, I., Spector, T. D., Bell, J. T., Hannon, E., Mill, J., Chauhan, G., Debette, S., Bis, J. C., Longstreth, W. T., Ikram, M. A., Launer, L. J., Seshadri, S., Jimenez-Conde, J., Cole, J. W., Schmidt, R., Słowik, A., Lemmens, R., Lindgren, A., Melander, O., Grewal, R. P., Sacco, R. L., Rundek, T., Rexrode, K., Arnett, D. K., Johnson, J. A., Benavente, O. R., Wasssertheil-Smoller, S., Lee, J. M., Pulit, S. L., Wong, Q., Rich, S. S., de Bakker, P. I., McArdle, P. F., Woo, D., Anderson, C. D., Xu, H., Heitsch, L., Fornage, M., Jern, C., Stefansson, K., Thorsteinsdottir, U., Gretarsdottir, S., Lewis, C. M., Sharma, P., Sudlow, C. L., Rothwell, P. M., Boncoraglio, G. B., Thijs, V., Levi, C., Meschia, J. F., Rosand, J., Kittner, S. J., Mitchell, B. D., Dichgans, M., Worrall, B. B., Markus, H. S., METASTROKE, U. K. Y. L. D. S., N. I. N.DS Stroke Genetics Network, Neurology Working Group of the CHARGE Consortium, M.nica Anne Hamilton-Bruce & Consortium, I. S. G. (2016). Genetic Variation at 16q24.2 is associated with small vessel stroke. Ann Neurol..

Richardson TG, Shihab HA, Hemani G, Zheng J, Hannon E, Mill J, Carnero-Montoro E, Bell JT, Lyttleton O, McArdle WL, Ring SM, Rodriguez S, Campbell C, Smith GD, Relton CL, Timpson NJ, Gaunt TR. Collapsed methylation quantitative trait loci analysis for low frequency and rare variants. Hum Mol Genet. Published ahead of print 2016 August. doi:10.1093/hmg/ddw283

Hannon E, Dempster E, Viana J, Burrage J, Smith AR, Macdonald R, St Clair D, Mustard C, Breen G, Therman S, Kaprio J, Toulopoulou T, Hulshoff Pol HE, Bohlken MM, Kahn RS, Nenadic I, Hultman CM, Murray RM, Collier DA, Bass N, Gurling H, McQuillin A, Schalkwyk L, Mill J. An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylationGenome Biology. 2016 17:176. doi:10.1186/s13059-016-1041-x

Jeffries AR, Uwanogho DA, Cocks G, Perfect LW, Dempster E, Mill J, Price J. Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogrammingRNA Published ahead of print  August 18, 2016. doi:10.1261/rna.058347.116

Houtepen LC, Vinkers CH, Carrillo-Roa T, Hiemstra M, van Lier PA, Meeus W, Branje S, Heim CM, Nemeroff CB, Mill J, Schalkwyk LC, Creyghton MP, Kahn RS, Joëls M, Binder EB, Boks MP. Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nat Commun. 2016 Mar. 7:10967. doi:10.1038/ncomms10967

Rijlaarsdam J, Pappa I, Walton E, Bakermans-Kranenburg MJ, Mileva-Seitz VR, Rippe RC, Roza SJ, Jaddoe VW, Verhulst FC, Felix JF, Cecil CA, Relton CL, Gaunt TR, McArdle W, Mill J, Barker ED, Tiemeier H, van IJzendoorn MH. An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication. Epigenetics. 2016 Feb. 11(2):140-9. doi:10.1080/15592294.2016.1145329.

Saundersona EA, Spiers H, Mifsuda KR, Gutierrez-Mecinasa M, Trollopea AF, Shaikha A, Mill J, Reula JMHM. 2016. Stress-induced gene expression and behavior are controlled by DNA methylation and methyl donor availability in the dentate gyrus. PNAS. Published ahead of print April 12. doi:10.1073/pnas.1524857113

Lunnon K, Hannon E, Smith RG, Dempster E, Wong C, Burrage J, Troakes C, Al-Sarraj S, Kepa A, Schalkwyk L, Mill J. 2016 Feb. Variation in 5-hydroxymethylcytosine across human cortex and cerebellumGenome Biol. 17(1):27. doi: 10.1186/s13059-016-0871-x. PMID: 26883014

Spiers H, Hannon E, Wells S, Williams B, Fernandes C, Mill J. Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. 2016 Feb. Mech Ageing Dev. pii: S0047-6374(16)30006-9. doi: 10.1016/j.mad.2016.02.001. [Epub ahead of print]. PMID: 26861500

Marzi SJ, Meaburn EL, Dempster EL, Lunnon K, Paya-Cano JL, Smith RG, Volta M, Troakes C, Schalkwyk LC, Mill J. 2016 Jan. Tissue-specific patterns of allelically-skewed DNA methylationEpigenetics. 19:1-12. PMID: 26786711

Lu AT, Hannon E, Levine ME, Hao K, Crimmins EM, Lunnon K, Kozlenkov A, Mill J, Dracheva S, Horvath S. 2016. Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum. Nat Commun. 7: 10561.

2015

Murphy TM, Tuzova AV, O’Rourke CJ, O’Meachair  S, Greene C, Sullivan L, Thornhill J, Barrett C, Loftus B, Lynch T, Perry AS. 2015. Multigene Methylation Biomarker Analysis in Prostate Cancer.  Epigenetic Diagnosis & Therapy. 1: 19-27.

Murphy TM, Wong CYC, Burrage J, Macdonald R, Moffitt T, Arseneault L, Caspi A, Mill J. 2015. Methylomic markers of persistent childhood asthma: a longitudinal study of asthma-discordant monozygotic twins. Clinical Epigenetics. 18;7:130.

Hannon ESpiers HViana JPidsley RBurrage JMurphy TMTroakes CTurecki G O’Donovan MCSchalkwyk LCBray NJ, Mill J. 2015. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk lociNature Neuroscience. [Epub ahead of print] DOI:10.1038/nn.4182.

Fisher HL*, Murphy TM*, Arseneault L, Caspi A, Moffitt TE, Viana J, Hannon E, Pidsley R, Burrage J, Dempster EL, Wong CC, Pariante CM, Mill J. 2015. Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms. Epigenetics. [Epub ahead of print] DOI:10.1080/15592294.2015.1099797 (*joint first authors)

Voyle N, Keohane A, Newhouse S, Lunnon K, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Hodges A, Kiddle S,Dobson RJ. 2015. A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer’s Disease Diagnosis. Journal of Alzheimer’s Disease. [Epub ahead of print] DOI: 10.3233/JAD-150440.

McDermott E, Ryan EJ, Tosetto M, Gibson D, Burrage J, Keegan D, Byrne K, Crowe E, Sexton G, Malone K, Harris RA, Kellermayer R, Mill J,Cullen G, Doherty GA, Mulcahy H, Murphy TM. 2015. DNA methylation profiling in inflammatory bowel disease provides new insights into disease pathogenesis. Journal of Crohn’s & Colitis. [Epub ahead of print] DOI: http://dx.doi.org/10.1093/ecco-jcc/jjv176.

Devall M, Burrage J, Caswell R, Johnson M, Troakes C, Al-Sarraj S, Jeffries AR, Mill J, Lunnon K. 2015. A comparison of mitochondrial DNA isolation methods in frozen post-mortem human brain tissue-applications for studies of mitochondrial genetics in brain disorders. Biotechniques. 59(4):241-6.

Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M,Vellas B, Hodges A, Lovestone S, Newhouse S, Dobson RJ, Kiddle SJ, Sattlecker M. 2015. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer’s Disease. Journal of Alzheimer’s Disease. 47(3):741-50.

Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJ, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, Hodges A, Timmons JA. 2015. A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. Genome Biol. 16:185.

Hannon E, Chand AN, Evans MD, Wong CC, Grubb MS, Mill J. 2015. A role for CaV1 and calcineurin signaling in depolarization-induced changes in neuronal DNA methylation. Neuroepigenetics 3:1-6.

Murphy TM, O’Donovan A, Mullins N, O’Farrelly C, McCann A, Malone K. 2015. Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes. Psychiatric Genetics. 25(2):71-8

Lunnon K, Smith RG, Cooper I, Greenbaum L, Mill J, Beeri MS. 2015. Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus. Neurobiology of aging 36(3): 1600 e1601-1604.

Spiers H, Hannon E, Schalkwyk LC, Smith R, Wong CC, O’Donovan MC, Bray NJ, Mill J. 2015. Methylomic trajectories across human fetal brain development. Genome research 25(3): 338-352.

Oh G, Wang SC, Pal M, Chen ZF, Khare T, Tochigi M, Ng C, Yang YA, Kwan A, Kaminsky ZA et al. 2015. DNA modification study of major depressive disorder: beyond locus-by-locus comparisons. Biol Psychiatry 77(3): 246-255.

Elliott G, Hong C, Xing X, Zhou X, Li D, Coarfa C, Bell RJ, Maire CL, Ligon KL, Sigaroudinia M et al. 2015. Intermediate DNA methylation is a conserved signature of genome regulation. Nature communications 6: 6363.

2014

De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C et al. 2014. Alzheimer’s disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature neuroscience 17(9): 1156-1163.

Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R et al. 2014. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer’s disease. Nature neuroscience 17(9): 1164-1170.

Cecil CA, Lysenko LJ, Jaffee SR, Pingault JB, Smith RG, Relton CL, Woodward G, McArdle W, Mill J, Barker ED. 2014. Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study. Mol Psychiatry 19(10): 1071-1077.

Sassi C, Guerreiro R, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C et al. 2014. Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer’s disease. Neurobiology of aging 35(10): 2422 e2413-2426.

Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M et al. 2014. Plasma proteins predict conversion to dementia from prodromal disease. Alzheimer’s & dementia : the journal of the Alzheimer’s Association 10(6): 799-807 e792.

Murphy TM, Mill J. 2014. Epigenetics in health and disease: heralding the EWAS era. Lancet 383(9933): 1952-1954.

Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S et al. 2014. Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Mol Psychiatry 19(1): 88-98.

Hodgson K, Tansey K, Dernovsek MZ, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D et al. 2014. Genetic differences in cytochrome P450 enzymes and antidepressant treatment response. J Psychopharmacol 28(2): 133-141.

Proitsi P, Lee SH, Lunnon K, Keohane A, Powell J, Troakes C, Al-Sarraj S, Furney S, Soininen H, Kloszewska I et al. 2014. Alzheimer’s disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood. Neurobiology of aging 35(2): 279-290.

Dempster EL, Wong CC, Lester KJ, Burrage J, Gregory AM, Mill J, Eley TC. 2014. Genome-wide methylomic analysis of monozygotic twins discordant for adolescent depression. Biol Psychiatry 76(12): 977-983.

Condliffe D, Wong A, Troakes C, Proitsi P, Patel Y, Chouliaras L, Fernandes C, Cooper J, Lovestone S, Schalkwyk L et al. 2014. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer’s disease brain. Neurobiology of aging 35(8): 1850-1854.

Van den Hove DL, Kompotis K, Lardenoije R, Kenis G, Mill J, Steinbusch HW, Lesch KP, Fitzsimons CP, De Strooper B, Rutten BP. 2014. Epigenetically regulated microRNAs in Alzheimer’s disease. Neurobiology of aging 35(4): 731-745.

Viana J, Pidsley R, Troakes C, Spiers H, Wong CC, Al-Sarraj S, Craig I, Schalkwyk L, Mill J. 2014. Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain. Epigenetics 9(4): 587-599.

Wong CC, Meaburn EL, Ronald A, Price TS, Jeffries AR, Schalkwyk LC, Plomin R, Mill J. 2014. Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol Psychiatry 19(4): 495-503.

Basil P, Li Q, Dempster EL, Mill J, Sham PC, Wong CC, McAlonan GM. 2014. Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain. Translational psychiatry 4: e434.

Bell JT, Loomis AK, Butcher LM, Gao F, Zhang B, Hyde CL, Sun J, Wu H, Ward K, Harris J et al. 2014. Differential methylation of the TRPA1 promoter in pain sensitivity. Nature communications 5: 2978.

Davies MN, Krause L, Bell JT, Gao F, Ward KJ, Wu H, Lu H, Liu Y, Tsai PC, Collier DA et al. 2014. Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biol 15(4): R56.

Devall M, Mill J, Lunnon K. 2014. The mitochondrial epigenome: a role in Alzheimer’s disease? Epigenomics 6(6): 665-675.

Fitzsimons CP, van Bodegraven E, Schouten M, Lardenoije R, Kompotis K, Kenis G, van den Hurk M, Boks MP, Biojone C, Joca S et al. 2014. Epigenetic regulation of adult neural stem cells: implications for Alzheimer’s disease. Molecular neurodegeneration 9: 25.

Ilott NE, Schneider T, Mill J, Schalkwyk L, Brolese G, Bizarro L, Stolerman IP, Dempster E, Asherson P. 2014. Long-term effects of gestational nicotine exposure and food-restriction on gene expression in the striatum of adolescent rats. PLoS One 9(2): e88896.

Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ et al. 2014. Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biol 15(10): 483.

Silva PN, Furuya TK, Braga IL, Rasmussen LT, Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payao SL et al. 2014. Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer’s disease patients. Journal of Alzheimer’s disease : JAD 38(1): 165-170.

Smith RG, Fernandes C, Kember R, Schalkwyk LC, Buxbaum J, Reichenberg A, Mill J. 2014. Transcriptomic changes in the frontal cortex associated with paternal age. Mol Autism 5(1): 24.

2013

Ouellet-Morin I, Wong CC, Danese A, Pariante CM, Papadopoulos AS, Mill J, Arseneault L. 2013. Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins. Psychol Med 43(9): 1813-1823.

Rommel AS, Halperin JM, Mill J, Asherson P, Kuntsi J. 2013. Protection from genetic diathesis in attention-deficit/hyperactivity disorder: possible complementary roles of exercise. Journal of the American Academy of Child and Adolescent Psychiatry 52(9): 900-910.

Barros M, Dempster EL, Illott N, Chabrawi S, Maior RS, Tomaz C, Silva MA, Huston JP, Mill J, Muller CP. 2013. Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys. Addict Biol 18(3): 452-454.

Shalev I, Moffitt TE, Sugden K, Williams B, Houts RM, Danese A, Mill J, Arseneault L, Caspi A. 2013. Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Mol Psychiatry 18(5): 576-581.

Smith RG, Reichenberg A, Kember RL, Buxbaum JD, Schalkwyk LC, Fernandes C, Mill J. 2013. Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: implications for neuropsychiatric disease. Mol Psychiatry 18(6): 635-636.

Dempster E, Viana J, Pidsley R, Mill J. 2013. Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future. Schizophr Bull 39(1): 11-16.

Murphy TM, Mullins N, Ryan M, Foster T, Kelly C, McClelland R, O’Grady J, Corcoran E, Brady J, Reilly M et al. 2013. Genetic variation in DNMT3B and increased global DNA methylation is associated with suicide attempts in psychiatric patients. Genes Brain Behav 12(1): 125-132.

O’Rourke CJ, Murphy TM, Hollywood D, Perry AS. 2013. Mining methylome databases. Trends in genetics : TIG 29(2): 63-65.

Pjetri E, Dempster E, Collier DA, Treasure J, Kas MJ, Mill J, Campbell IC, Schmidt U. 2013. Quantitative promoter DNA methylation analysis of four candidate genes in anorexia nervosa: a pilot study. Journal of psychiatric research 47(2): 280-282.

Lunnon K, Mill J. 2013. Epigenetic studies in Alzheimer’s disease: current findings, caveats, and considerations for future studies. Am J Med Genet B Neuropsychiatr Genet 162B(8): 789-799.

Melas PA, Wei Y, Wong CC, Sjoholm LK, Aberg E, Mill J, Schalling M, Forsell Y, Lavebratt C. 2013. Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum 16(7): 1513-1528.

Mill J, Heijmans BT. 2013. From promises to practical strategies in epigenetic epidemiology. Nature reviews Genetics 14(8): 585-594.

Perry AS, O’Hurley G, Raheem OA, Brennan K, Wong S, O’Grady A, Kennedy AM, Marignol L, Murphy TM, Sullivan L et al. 2013. Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer. International journal of cancer Journal international du cancer 132(8): 1771-1780.

Leung R, Proitsi P, Simmons A, Lunnon K, Guntert A, Kronenberg D, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I et al. 2013. Inflammatory proteins in plasma are associated with severity of Alzheimer’s disease. PLoS One 8(6): e64971.

Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H et al. 2013. A blood gene expression marker of early Alzheimer’s disease. Journal of Alzheimer’s disease : JAD 33(3): 737-753.

Pidsley R, CC YW, Volta M, Lunnon K, Mill J, Schalkwyk LC. 2013. A data-driven approach to preprocessing Illumina 450K methylation array data. BMC genomics 14: 293.

Powell TR, Smith RG, Hackinger S, Schalkwyk LC, Uher R, McGuffin P, Mill J, Tansey KE. 2013. DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP. Translational psychiatry 3: e300.

Silva PN, Furuya TK, Sampaio Braga I, Rasmussen LT, de Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payao SL et al. 2013. CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer’s disease patients. Journal of Alzheimer’s disease : JAD 33(2): 349-355.

2012

Jeffries, A.R., Perfect, L.W., Ledderose, J., Schalkwyk, L.C., Bray, N.J., Mill, J., and Price, J. (2012). Stochastic choice of allelic expression in human neural stem cells. Stem cells 30, 1938-1947.

Sullivan L, Murphy TM, Barrett C, Loftus B, Thornhill J, Lawler M, Hollywood D, Lynch T, Perry AS. 2012. IGFBP7 promoter methylation and gene expression analysis in prostate cancer. The Journal of urology 188(4): 1354-1360.

Huezo-Diaz P, Perroud N, Spencer EP, Smith R, Sim S, Virding S, Uher R, Gunasinghe C, Gray J, Campbell D et al. 2012. CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP. J Psychopharmacol 26(3): 398-407.

Davies, M., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, R.A., Milosavljevic, A., Troakes, C., et al. (2012). Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol 13, R43.

Kember, R.L., Dempster, E.L., Lee, T.H., Schalkwyk, L.C., Mill, J., and Fernandes, C. (2012). Maternal separation is associated with strain-specific responses to stress and epigenetic alterations to Nr3c1, Avp, and Nr4a1 in mouse. Brain and behavior 2, 455-467.

Boks MP, de Jong NM, Kas MJ, Vinkers CH, Fernandes C, Kahn RS, Mill J, Ophoff RA. 2012. Current status and future prospects for epigenetic psychopharmacology. Epigenetics 7(1).

Clarke TK, Dempster E, Docherty SJ, Desrivieres S, Lourdsamy A, Wodarz N, Ridinger M, Maier W, Rietschel M, Schumann G. 2012. Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse. Addict Biol 17(1): 202-208.

Xie W, Barr CL, Kim A, Yue F, Lee AY, Eubanks J, Dempster EL, Ren B. 2012. Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 148(4): 816-831.

Pidsley R, Dempster E, Troakes C, Al-Sarraj S, Mill J. 2012a. Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight. Epigenetics 7(2): 155-163.

Heijmans, B.T., and Mill, J. (2012). Commentary: The seven plagues of epigenetic epidemiology. Int J Epidemiol 41, 74-78.

Dempster, E., Viana, J., Pidsley, R., and Mill, J. (2012). Epigenetic Studies of Schizophrenia: Progress, Predicaments, and Promises for the Future. Schizophr Bull.

Mizuno, K., Dempster, E., Mill, J., and Giese, K.P. (2012). Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning. Genes Brain Behav 11, 651-659.

Bell, J.T., Tsai, P.C., Yang, T.P., Pidsley, R., Nisbet, J., Glass, D., Mangino, M., Zhai, G., Zhang, F., Valdes, A., et al. (2012). Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS genetics 8, e1002629.

Pidsley R, Fernandes C, Viana J, Paya-Cano JL, Liu L, Smith RG, Schalkwyk LC, Mill J. 2012. DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice. Mol Brain 5: 42.

2011

Barclay NL, Eley TC, Mill J, Wong CC, Zavos HM, Archer SN, Gregory AM. 2011. Sleep quality and diurnal preference in a sample of young adults: associations with 5HTTLPR, PER3, and CLOCK 3111. Am J Med Genet B Neuropsychiatr Genet 156B(6): 681-690.

Pidsley, R., and Mill, J. (2011). Research Highlights: epigenetic changes to serotonin receptor gene expression in schizophrenia and bipolar disorder. Epigenomics 3, 537-538.

Edwards A, Treiber CD, Breuss M, Pidsley R, Huang GJ, Cleak J, Oliver PL, Flint J, Keays DA. 2011. Cytoarchitectural Disruption of the Superior Colliculus and an Enlarged Acoustic Startle Response in the Tuba1a Mutant Mouse. Neuroscience 195: 191-200.

Barros, M., Dempster, E.L., Illott, N., Chabrawi, S., Maior, R.S., Tomaz, C., De Souza Silva, M.A., Huston, J.P., Mill, J., and Muller, C.P. (2011). Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys. Addict Biol.

Furney SJ, Simmons A, Breen G, Pedroso I, Lunnon K, Proitsi P, Hodges A, Powell J, Wahlund LO, Kloszewska I et al. 2011. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer’s disease. Mol Psychiatry 16(11): 1130-1138.

Wong, C.C., Mill, J., and Fernandes, C. (2011). Drugs and addiction: an introduction to epigenetics. Addiction 106, 480-489.

Voineagu, I., Wang, X., Johnston, P., Lowe, J.K., Tian, Y., Horvath, S., Mill, J., Cantor, R.M., Blencowe, B.J., and Geschwind, D.H. (2011). Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature 474, 380-384.

Lunnon K, Teeling JL, Tutt AL, Cragg MS, Glennie MJ, Perry VH. 2011. Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration. J Immunol 186(12): 7215-7224.

Kaminsky, Z., Tochigi, M., Jia, P., Pal, M., Mill, J., Kwan, A., Ioshikhes, I., Vincent, J.B., Kennedy, J.L., Strauss, J., et al. (2011). A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder. Mol Psychiatry.

Desrivieres S, Lourdusamy A, Muller C, Ducci F, Wong CP, Kaakinen M, Pouta A, Hartikainen AL, Isohanni M, Charoen P et al. 2011. Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents. Addict Biol 16(3): 510-513.

Mill, J. (2011). Toward an integrated genetic and epigenetic approach to Alzheimer’s disease. Neurobiology of aging 32, 1188-1191.

Pidsley, R., and Mill, J. (2011). Epigenetic studies of psychosis: current findings, methodological approaches, and implications for postmortem research. Biol Psychiatry 69, 146-156.

Murphy TM, Sullivan L, Lane C, O’Connor L, Barrett C, Hollywood D, Lynch T, Lawler M, Perry AS. 2011a. In silico analysis and DHPLC screening strategy identifies novel apoptotic gene targets of aberrant promoter hypermethylation in prostate cancer. The Prostate 71(1): 1-17.

Campbell, I.C., Mill, J., Uher, R., and Schmidt, U. (2011). Eating disorders, gene-environment interactions and epigenetics. Neurosci Biobehav Rev 35, 784-793.

Dempster, E.L., Pidsley, R., Schalkwyk, L.C., Owens, S., Georgiades, A., Kane, F., Kalidindi, S., Picchioni, M., Kravariti, E., Toulopoulou, T., et al. (2011).Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet 20, 4786-4796.

Engmann, O., Hortobagyi, T., Pidsley, R., Troakes, C., Bernstein, H.G., Kreutz, M.R., Mill, J., Nikolic, M., and Giese, K.P. (2011). Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition. Brain 134, 2408-2421.

Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N et al. 2011. Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness. Am J Psychiatry 168(4): 408-417.

Keers R, Uher R, Huezo-Diaz P, Smith R, Jaffee S, Rietschel M, Henigsberg N, Kozel D, Mors O, Maier W et al. 2011. Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project. Pharmacogenomics J 11(2): 138-145.

Murphy TM, Ryan M, Foster T, Kelly C, McClelland R, O’Grady J, Corcoran E, Brady J, Reilly M, Jeffers A et al. 2011b. Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms. Behav Brain Funct 7: 22.

Smith R, Mill J. 2011. Epigenetics and Chronic Diseases: An Overview. In Epigenetic Aspects of Chronic Disease, Vol 1. Springer.

Wong, C.C., Caspi, A., Williams, B., Houts, R., Craig, I.W., and Mill, J. (2011). A longitudinal twin study of skewed X chromosome-inactivation. PLoS One 6, e17873.

2010

Pidsley, R., Dempster, E.L., and Mill, J. (2010). Brain weight in males is correlated with DNA methylation at IGF2. Mol Psychiatry 15(9), 880-881.

Meaburn, E.L., Schalkwyk, L.C., and Mill, J. (2010). Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics 5, 578-582.

Amstadter AB, Balachandar V, Bergen SE, Ceulemans S, Christensen JH, Cole J, Dagdan E, De Luca V, Ducci F, Tee SF et al. 2010. Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009. Psychiatr Genet 20(5): 229-268.

Bell, C.G., Finer, S., Lindgren, C.M., Wilson, G.A., Rakyan, V.K., Teschendorff, A.E., Akan, P., Stupka, E., Down, T.A., Prokopenko, I., et al. (2010).Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus. PLoS One 5.

Docherty, S.J., Davis, O.S., Haworth, C.M., Plomin, R., and Mill, J. (2010). DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA. Methods 52, 255-258.

Lundstrom, S., Haworth, C.M., Carlstrom, E., Gillberg, C., Mill, J., Rastam, M., Hultman, C.M., Ronald, A., Anckarsater, H., Plomin, R., et al. (2010).Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies. J Child Psychol Psychiatry 51, 850-856.

Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Guntert A et al. 2010. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch Gen Psychiatry 67(7): 739-748.

Dempster EL, Kiss E, Kapornai K, Daroczi G, Mayer L, Baji I, Tamas Z, Gadoros J, Kennedy JL, Vetro A et al. 2010. No evidence of an association between two genes, EDN1 and ACE, and childhood-onset mood disorders. Am J Med Genet B Neuropsychiatr Genet 153B(1): 341-346.

Schalkwyk, L.C., Meaburn, E.L., Smith, R., Dempster, E.L., Jeffries, A.R., Davies, M.N., Plomin, R., and Mill, J. (2010). Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet 86(2), 196-212.

Asuni AA, Hilton K, Siskova Z, Lunnon K, Reynolds R, Perry VH, O’Connor V. 2010. Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease. Neuroscience 165(3): 662-674.

Wong, C.C., Caspi, A., Williams, B., Craig, I.W., Houts, R., Ambler, A., Moffitt, T.E., and Mill, J. (2010). A longitudinal study of epigenetic variation in twins. Epigenetics 5(6), 516-526.

Drago A, Serretti A, Smith R, Huezo-Diaz P, Malitas P, Albani D, Ronchi DD, Pae C-U, Aitchison KJ. 2010. No association between genetic markers in BDNF gene and lithium prophylaxis in a Greek sample. International Journal of Psychiatry in Clinical Practice 14(2): 154-157.

Keays DA, Cleak J, Huang GJ, Edwards A, Braun A, Treiber CD, Pidsley R, Flint J. 2010. The Role of Tuba1a in Adult Hippocampal Neurogenesis and the Formation of the Dentate Gyrus. Developmental Neuroscience 32(4): 268-277.

2009

Mill J, Wigg K, Burcescu I, Vetro A, Kiss E, Kapornai K, Tamas Z, Baji I, Gadoros J, Kennedy JL et al. 2009. Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood-onset mood disorders (COMD). Am J Med Genet B Neuropsychiatr Genet 150B(6): 866-873.

Dutt A, McDonald C, Dempster E, Prata D, Shaikh M, Williams I, Schulze K, Marshall N, Walshe M, Allin M et al. 2009. The effect of COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes on hippocampal and lateral ventricular volume in psychosis. Psychol Med 39(11): 1783-1797.

Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N et al. 2009. Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project. Neuropsychopharmacology 34(12): 2517-2528.

Rutten, B.P., and Mill, J. (2009). Epigenetic mediation of environmental influences in major psychotic disorders. Schizophr Bull 35(6), 1045-1056.

Huezo-Diaz P, Uher R, Smith R, Rietschel M, Henigsberg N, Marusic A, Mors O, Maier W, Hauser J, Souery D et al. 2009. Moderation of antidepressant response by the serotonin transporter gene. Br J Psychiatry 195(1): 30-38.

Cunningham C, Campion S, Lunnon K, Murray CL, Woods JF, Deacon RM, Rawlins JN, Perry VH. 2009. Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease. Biol Psychiatry 65(4): 304-312.

Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N et al. 2009. Genetic predictors of response to antidepressants in the GENDEP project. Pharmacogenomics J 9(4): 225-233.

Docherty, S.J., Davis, O.S., Haworth, C.M., Plomin, R., and Mill, J. (2009). Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation. Epigenetics Chromatin 2(1), 3.

Hanif M, Sneddon PH, Al-Ahmadi FM, Reid N. 2009. The perceptions, views and opinions of university students about physics learning during undergraduate laboratory work. European Journal of Physics 30(1): 85.

Mill J, Petronis A. 2009. Profiling DNA methylation from small amounts of genomic DNA starting material: efficient sodium bisulfite conversion and subsequent whole-genome amplification. Methods Mol Biol 507: 371-381.

Reichenberg, A., Mill, J., and MacCabe, J.H. (2009). Epigenetics, genomic mutations and cognitive function. Cogn Neuropsychiatry 14(4-5), 377-390.

Smith, R.G., Kember, R.L., Mill, J., Fernandes, C., Schalkwyk, L.C., Buxbaum, J.D., and Reichenberg, A. (2009). Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model. PLoS One 4(12), e8456.

Xu X, Mill J, Sun B, Chen CK, Huang YS, Wu YY, Asherson P. 2009. Association study of promoter polymorphisms at the dopamine transporter gene in Attention Deficit Hyperactivity Disorder. BMC Psychiatry 9: 3.

2008

Wong CC, Schumann G. 2008. Review. Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders. Philos Trans R Soc Lond B Biol Sci 363(1507): 3213-3222.

Mill J, Kiss E, Baji I, Kapornai K, Daroczy G, Vetro A, Kennedy J, Kovacs M, Barr C. 2008a. Association study of the estrogen receptor alpha gene (ESR1) and childhood-onset mood disorders. Am J Med Genet B Neuropsychiatr Genet 147B(7): 1323-1326.

Mill, J., and Petronis, A. (2008). Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility. J Child Psychol Psychiatry 49(10), 1020-1030.

Mill, J., Tang, T., Kaminsky, Z., Khare, T., Yazdanpanah, S., Bouchard, L., Jia, P., Assadzadeh, A., Flanagan, J., Schumacher, A., et al. (2008). Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet 82(3), 696-711.

Murphy TM, Perry AS, Lawler M. 2008. The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer. Endocrine-related cancer 15(1): 11-25.

Brookes KJ, Neale B, Xu X, Thapar A, Gill M, Langley K, Hawi Z, Mill J, Taylor E, Franke B et al. 2008. Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth. Am J Med Genet B Neuropsychiatr Genet 147B(1): 94-99.

Bramon E, Dempster E, Frangou S, Shaikh M, Walshe M, Filbey FM, McDonald C, Sham P, Collier DA, Murray R. 2008. Neuregulin-1 and the P300 waveform–a preliminary association study using a psychosis endophenotype. Schizophr Res 103(1-3): 178-185.

M M, M B, M T, M V. 2008. Primary adrenal leiomyosarcoma: a case report and literature review. Clin Med Oncol 2: 353-356.

2007

Mill, J., and Petronis, A. (2007). Molecular studies of major depressive disorder: the epigenetic perspective. Mol Psychiatry 12(9), 799-814.

Dempster EL, Burcescu I, Wigg K, Kiss E, Baji I, Gadoros J, Tamas Z, Kennedy JL, Vetro A, Kovacs M et al. 2007a. Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders. Arch Gen Psychiatry 64(10): 1189-1195.

Mill J. 2007. Rodent models: utility for candidate gene studies in human attention-deficit hyperactivity disorder (ADHD). J Neurosci Methods 166(2): 294-305.

Xu X, Mill J, Zhou K, Brookes K, Chen CK, Asherson P. 2007. Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples. Am J Med Genet B Neuropsychiatr Genet 144B(1): 83-86.

Dempster EL, Kiss E, Kapornai K, Daroczy G, Mayer L, Baji I, Tamas Z, Gadoros J, Kennedy JL, Vetro A et al. 2007b. No evidence of association between a functional polymorphism in the MTHFR gene and childhood-onset mood disorders. Mol Psychiatry 12(12): 1063-1064.

2006

Dempster EL, Toulopoulou T, McDonald C, Bramon E, Walshe M, Wickham H, Sham PC, Murray RM, Collier DA. 2006a. Episodic memory performance predicted by the 2bp deletion in exon 6 of the “alpha 7-like” nicotinic receptor subunit gene. Am J Psychiatry 163(10): 1832-1834.

Mill, J., Yazdanpanah, S., Guckel, E., Ziegler, S., Kaminsky, Z., and Petronis, A. (2006). Whole genome amplification of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources.Biotechniques 41(5): 603-607.

Mill, J., Dempster, E., Caspi, A., Williams, B., Moffitt, T., and Craig, I. (2006). Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. Am J Med Genet B Neuropsychiatr Genet 141B(4): 421-425.

Bramon E, Dempster E, Frangou S, McDonald C, Schoenberg P, MacCabe JH, Walshe M, Sham P, Collier D, Murray RM. 2006. Is there an association between the COMT gene and P300 endophenotypes? Eur Psychiatry 21(1): 70-73.

Brookes KJ, Mill J, Guindalini C, Curran S, Xu X, Knight J, Chen CK, Huang YS, Sethna V, Taylor E et al. 2006. A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy. Arch Gen Psychiatry 63(1): 74-81.

Fernandes C, Hoyle E, Dempster E, Schalkwyk LC, Collier DA. 2006. Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory. Genes Brain Behav 5(6): 433-440.

Mill J, Caspi A, Williams BS, Craig I, Taylor A, Polo-Tomas M, Berridge CW, Poulton R, Moffitt TE. 2006c. Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. Arch Gen Psychiatry 63(4): 462-469.

Dempster, E.L., Mill, J., Craig, I.W., and Collier, D.A. (2006). The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet 7: 10.

2005

Cunningham C, Wilcockson DC, Campion S, Lunnon K, Perry VH. 2005. Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration. J Neurosci 25(40): 9275-9284.

Xu X, Mill J, Chen CK, Brookes K, Taylor E, Asherson P. 2005a. Family-based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: no evidence for association in UK and Taiwanese samples. Am J Med Genet B Neuropsychiatr Genet 139B(1): 11-13.

Mill J, Xu X, Ronald A, Curran S, Price T, Knight J, Craig I, Sham P, Plomin R, Asherson P. 2005a. Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B. Am J Med Genet B Neuropsychiatr Genet 133B(1): 68-73.

Dempster E, Toulopoulou T, McDonald C, Bramon E, Walshe M, Filbey F, Wickham H, Sham PC, Murray RM, Collier DA. 2005. Association between BDNF val66 met genotype and episodic memory. Am J Med Genet B Neuropsychiatr Genet 134B(1): 73-75.

Xu X, Knight J, Brookes K, Mill J, Sham P, Craig I, Taylor E, Asherson P. 2005b. DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association. Am J Med Genet B Neuropsychiatr Genet 134B(1): 115-118.

Mill J, Asherson P, Craig I, D’Souza UM. 2005b. Transient expression analysis of allelic variants of a VNTR in the dopamine transporter gene (DAT1). BMC Genet 6: 3.

Mill J, Sagvolden T, Asherson P. 2005c. Sequence analysis of Drd2, Drd4, and Dat1 in SHR and WKY rat strains. Behav Brain Funct 1: 24.

2004

D’Souza UM, Russ C, Tahir E, Mill J, McGuffin P, Asherson PJ, Craig IW. 2004. Functional effects of a tandem duplication polymorphism in the 5’flanking region of the DRD4 gene. Biol Psychiatry 56(9): 691-697.

Mill J, Curran S, Richards S, Taylor E, Asherson P. 2004a. Polymorphisms in the dopamine D5 receptor (DRD5) gene and ADHD. Am J Med Genet B Neuropsychiatr Genet 125B(1): 38-42.

Lowe N, Kirley A, Hawi Z, Sham P, Wickham H, Kratochvil CJ, Smith SD, Lee SY, Levy F, Kent L et al. 2004. Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. Am J Hum Genet 74(2): 348-356.

Craig IW, Mill J, Craig GM, Loat C, Schalkwyk LC. 2004. Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes. Eur J Hum Genet 12(8): 639-646.

Mill J, Richards S, Knight J, Curran S, Taylor E, Asherson P. 2004b. Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD. Mol Psychiatry 9(8): 801-810.

2003

Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A et al. 2003. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301(5631): 386-389.

Freeman B, Smith N, Curtis C, Huckett L, Mill J, Craig IW. 2003. DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping. Behav Genet 33(1): 67-72.

Mill J, Fisher N, Curran S, Richards S, Taylor E, Asherson P. 2003. Polymorphisms in the dopamine D4 receptor gene and attention-deficit hyperactivity disorder. Neuroreport 14(11): 1463-1466.

Chen CK, Chen SL, Mill J, Huang YS, Lin SK, Curran S, Purcell S, Sham P, Asherson P. 2003. The dopamine transporter gene is associated with attention deficit hyperactivity disorder in a Taiwanese sample. Mol Psychiatry 8(4): 393-396.

2002

Holmes J, Payton A, Barrett J, Harrington R, McGuffin P, Owen M, Ollier W, Worthington J, Gill M, Kirley A et al. 2002. Association of DRD4 in children with ADHD and comorbid conduct problems. Am J Med Genet 114(2): 150-153.

Mill J, Asherson P, Browes C, D’Souza U, Craig I. 2002a. Expression of the dopamine transporter gene is regulated by the 3′ UTR VNTR: Evidence from brain and lymphocytes using quantitative RT-PCR. Am J Med Genet 114(8): 975-979.

Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R. 2002. Role of genotype in the cycle of violence in maltreated children. Science 297(5582): 851-854.

Mill J, Galsworthy MJ, Paya-Cano JL, Sluyter F, Schalkwyk LC, Plomin R, Asherson P. 2002b. Home-cage activity in heterogeneous stock (HS) mice as a model of baseline activity. Genes Brain Behav 1(3): 166-173.

Mill J, Curran S, Kent L, Gould A, Huckett L, Richards S, Taylor E, Asherson P. 2002c. Association study of a SNAP-25 microsatellite and attention deficit hyperactivity disorder. Am J Med Genet 114(3): 269-271.

Mill JS, Caspi A, McClay J, Sugden K, Purcell S, Asherson P, Craig I, McGuffin P, Braithwaite A, Poulton R et al. 2002d. The dopamine D4 receptor and the hyperactivity phenotype: a developmental-epidemiological study. Mol Psychiatry 7(4): 383-391.

2001

Curran S, Mill J, Sham P, Rijsdijk F, Marusic K, Taylor E, Asherson P. 2001a. QTL association analysis of the DRD4 exon 3 VNTR polymorphism in a population sample of children screened with a parent rating scale for ADHD symptoms. Am J Med Genet 105(4): 387-393.

Curran S, Mill J, Tahir E, Kent L, Richards S, Gould A, Huckett L, Sharp J, Batten C, Fernando S et al. 2001b. Association study of a dopamine transporter polymorphism and attention deficit hyperactivity disorder in UK and Turkish samples. Mol Psychiatry 6(4): 425-428.

Mill J, Curran S, Kent L, Richards S, Gould A, Virdee V, Huckett L, Sharp J, Batten C, Fernando S et al. 2001. Attention deficit hyperactivity disorder (ADHD) and the dopamine D4 receptor gene: evidence of association but no linkage in a UK sample. Mol Psychiatry 6(4): 440-444.

1999

Dempster EL, Pryor KV, Francis D, Young JE, Rogers HJ. 1999. Rapid DNA extraction from ferns for PCR-based analyses. Biotechniques 27(1): 66-68.