Methylome, sweet methylome
After the Human Genome Project revealed that humans had roughly the same number of genes as a fruit fly, attention rapidly refocused on gene regulation, with the realisation that control of gene expression was a key factor in human biology (and disease). In particular, work on epigenetic modifications of DNA and histones has exploded in popularity. Based at Exeter and King’s College London, Jonathan Mill is examining modifications to DNA – particularly cytosine methylation – in the human brain, and the potential consequences it could have for both neurodevelopmental and neurodegenerative disorders.
Read the full BNA article here