Entries by Jonathan Mill
Barry Chioza
Barry Chioza is a Research Fellow working at the University of Exeter Medical School. Barry obtained an Honours degree in Biochemistry from Aberystwyth University before going to King’s College London to complete a M.Sc. in Neuroscience, followed by a Ph.D. in Molecular Genetics in 2002, entitled “Identification of genes involved in idiopathic generalised epilepsy”. The […]
Rob Flynn
My name is Rob Flynn and I am from Galway, Ireland. I acquired a BA in psychology from University College Dublin during which time I spent summers in Nice, France (2015) and New York (2016) working and travelling. Following my bachelor, I wanted to learn more about the fundamental underpinnings of many neurobiological diseases. To this […]
New study uses DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits
A new paper from our group published in the American Journal of Human Genetics highlights the utility of DNA methylation quantitative trait loci (mQTLs), for interpreting the functional consequences of common genetic variation associated with human traits. We describe the first comprehensive analysis of common genetic variation on DNA methylation using the Illumina EPIC array […]
Widespread H3K27ac differences associated with Alzheimer’s disease in the entorhinal cortex
Building on our previous work exploring DNA methylation in Alzheimer’s disease (AD), a new paper from our group just published in Nature Neuroscience has identified extensive differences in the histone modification H3K27ac associated with AD neuropathology. We quantified genome-wide patterns of H3K27ac in entorhinal cortex samples from AD cases and matched controls using chromatin immunoprecipitation […]
Greg Wheildon
“I graduated with a BSc in Pharmacology from the University of Bristol and spent time afterwards helping with the management of my family’s business. I returned to academia to study for a MSc in Molecular Neuroscience, also at the University of Bristol. It was here that my interest in dementia research grew and my research […]
Adam Smith
Research Fellow University of Exeter – College of Medicine and Health Adam graduated in Medical Sciences at the University of Exeter College of Medicine and Health, in 2014, where he found a particular interest in genetics and neurology. Adam spent a year as an associate genetic technician for the Royal Devon and Exeter Genetic NHS […]
Exeter secures international autism research grant
A three year international research grant of $975,000 USD (almost £750,000) has been awarded to the University of Exeter for research by Professor Jonathan Mill into the genetics of autism. The Simons Foundation Autism Research Initiative (SFARI) awarded the grant to Mill, who heads the Complex Disease Epigenomics Group at the University of Exeter Medical […]
Major funding to explore genomic changes in dementia
Exeter researchers will join forces with global experts to investigate the mechanisms behind Alzheimer’s disease, in a project announced on World Alzheimer’s Day (September 21). The Exeter team, led by Professor Jonathan Mill, has been awarded almost £450,000 by Alzheimer’s Research UK (ARUK) to research the genomic mechanisms involved in progression of the disease. The […]
Twin study highlights importance of both genetics and environment on gene activity
New research highlights the extent to which epigenetic variation is influenced by both inherited and environmental factors. Epigenetic processes affect the expression or activity of genes without changing the underlying DNA sequence and are believed to be one mechanism by which the environment can interact with the genome. Now, an international group of researchers including […]