Entries by Jonathan Mill

New MRC funding to study genomic changes in schizophrenia brain

The Medical Research Council has funded us to continue our research into the genomic underpinnings of schizophrenia. The project will use cutting-edge methods to profile gene regulation (DNA modifications, histone modifications, gene expression, alternative splicing) in purified neuronal nuclei isolated from a unique collection of post-mortem brain samples. Given the evidence for a neurodevelopmental component […]

Dorothea Seiler Vellame

Thea graduated with a degree in Mathematics from the University of Exeter in 2017. In 2016, she carried out a BBSRC funded Bioinformatics Research Placement at the University of Manchester, in which she studied the recombination of the Human Immunodeficiency Virus (HIV). She is a bioinformatics PhD student in the University of Exeter College of […]

Szi Kay Leung

Szi Kay Leung is a Postdoctoral Research Fellow at the University of Exeter. Prior to this, she graduated with an integrated MBiochem in Biochemistry from the University of Oxford where she completed her final year project at NDORMS (Nuffield Department of Orthopaedics, Rheumatology and Musculosketal Sciences) on the regulation of Nerve Growth Factor, pain mediator, […]

Gemma Shireby

Gemma Shireby is a PhD student at the University of Exeter, under the supervision of Professor Jonathon Mill and Dr Eilis Hannon. She graduated with a first class degree in BSc biology with psychology from Queen Mary, University of London and went on to study an MSc in “Genes, environment and development” at King’s College […]

Georgina Mansell

Georgina graduated from the University of Exeter with a first class degree in Natural Sciences in 2017. During this time, she studied a wide range of topics in science and mathematics and discovered her interest in programming. In her final year project, she chose to work on a bioinformatics project with Dr Eilis Hannon in […]

New paper highlights how DNA hydroxymethylation in the human brain change during development.

Previous work from our group described dynamic changes in DNA methylation (5mC) occurring during human fetal brain development. Other epigenetic processes operating during this period have not been extensively explored – of particular interest is DNA hydroxymethylation (5hmC), a modification that we have found to be enriched in the human brain, and which is hypothesized […]

Clare Davis

Clare Davis is a third year BSc Medical Sciences (Neuroscience) student at the University of Exeter. She is now currently on her Professional Training Year, where she will be assisting with Dr. Asami Ogoro-Ando and Dr. John Chilton’s research. Her project is titled “Defining the molecular actions of JAKMIP1, a neuronal translation regulator, identified as […]

Madie Eve

Madie Eve has just completed her second year at the University of Exeter studying Medical Sciences. She is hoping to use this year of research to understand more about the neuropathology associated with Autism in Dr Asami Oguro-Ando’s laboratory as a PTY student.